Joan Cusack
Rachel Bitterman
Matthew Lillard
Luc Fromage
Whoopi Goldberg
Daniel's 'Boss'
Mel Brooks
Joe Snow (voice)
Chantal Strand
Nancy Nut-What
Dave Ward
Sally Ann Santa Claus
Steve Whitmire
Kermit the Frog / Rizzo the Rat / Beaker / Elvises (voice)
Dave Goelz
The Great Gonzo / Dr. Bunsen Honeydew / Waldorf / Zoot (voice)
Bill Barretta
Pepe the King Prawn / Bobo the Bear / Johnny Fiama / Swedish Chef / Lew Zealand / Howard Tubman / Rowlf the Dog / Elvises (voice)
Eric Jacobson
Miss Piggy / Fozzie Bear / Animal / Yoda / Elvises (voice)
Brian Henson
Scooter / Janice / Sal Minella (voice)
Kevin Clash
Sam Eagle (voice)
John Henson
Sweetums (voice)
John Kennedy
Dr. Teeth (voice)
Jerry Nelson
Robin the Frog / Statler / Floyd Pepper / Announcer / Crazy Harry / Pops
Allan Trautman
Eugene the Tuba Player (voice)
Zach Braff
Dr. John "J.D." Dorian
Sarah Chalke
Dr. Elliot Reid
John C. McGinley
Dr. Perry Cox
Judy Reyes
Nurse Carla Espinosa
Robert Smigel
Triumph, the Insult Comic Dog (voice)